EarlyCause

Causative mechanisms & integrative models linking early-life-stress to psycho-cardio-metabolic multi-morbidity

OBJECTIVES

Identify causative mechanisms linking early life stress (ELS) to depression, diabetes and heart disease, and their multi-morbidity
Identify biological mediators and environmental moderators of the impact of ELS on disease and multi-morbidity development
Perform multi-level data integration to derive new predictive tools, multi-factorial signatures and life-course models of multi-morbidity development
Establish an open-access research platform and best practices for accelerating future research on ELS

ROLES

Coordinate and manage the EarlyCause project
Build integrative causative models of disease and multi-morbidity development
Build and demonstrate artificial intelligence solutions for predicting ELS-induced disease and multi-morbidity

PARTNERS

NO.	INSTITUTION	COUNTRY
1	University of Barcelona	Spain
2	European Molecular Biology Lab. European Bioinformatics Institute	Germany
3	University of Zurich	Switzerland
4	King's College London	United Kingdom
5	Consejo Superior de Investigadores científicas	Spain
6	Centre Européen de Recherche en Biologie et Médicine	France
7	University of Oulu	Finland
8	Istituto di Ricovero e Cura a Carattere Scientifico - Fatebenefratelli	Italy
9	University of Bristol	United Kingdom
10	VU Amsterdam Medical Centre	Nederland
11	Empiricia GmbH	Germany
12	Universitat Pompeu Fabra	Spain
13	Combinostic Oy	Finland